Isolation Valves

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Optional Components

CoolCube™ Control Module

Mounting Hardware

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Our Solenoid Operated Isolation Valves offer instrument designers a completely inert, non-metallic fluid path. The valves use a flexible diaphragm to isolate the solenoid actuation mechanism from the fluid path. Isolation Valves offer low internal volumes, precise flow control and excellent ease of installation making them particularly suitable for use in highly aggressive and / or high purity fluid applications such as analytical chemistry and clinical diagnostics. The highly inert fluid path is especially useful in liquid chromatography, genomics and protein synthesis applications. The high flow factor makes these valves well suited to environmental and water analysis applications.

Technical Features

  • 12 volt or 24 volt DC solenoid
  • Valve configurations
    • 2 way normally closed, 2 way normally open, and 3 way
  • Inert materials
    • Body materials:  PTFE, PEEK & PPS
    • Diaphragm materials:  PTFE, FFKM & EPDM
  • Valve orifice sizes range from 0.032” to 0.125”

Standard Product Configuration:

The following table shows the available technical aspects of our standard isolation valves.

Customization available upon request.

Model 038T 039T 075T2 075T3 079T 100T2 100T3 179T
Solenoid Diameter in 0.38 0.38 0.75 0.75 0.75 1.00 1.00 1.00
Configuration Normally Open
Normally Closed
Manifold Mount
Voltage 12
Max Pressure (psi) 10
Body Material PTFE
Diaphragm Material PTFE
Orifice Size(in.)

Internal Volume(µl)

0.032 18 13 19 45 21 47
0.042 55
0.046 52
0.054 35 21
0.062 54 31 55 87
0.092 133
0.125 296

Visit our Download Center to obtain product literature, drawings, and models.  Contact us for help in selecting the correct Isolation Valve for your application.


Bio-Chem Valve™ Isolation Valves are available in three different configurations; normally closed, normally open and 3-way.

When the isolation valve is energized, the solenoid retracts the armature that is attached to a flexible diaphragm. In a normally closed valve, this raises the diaphragm allowing fluid to flow between the inlet and outlet ports.

For a normally open isolation valve, the operation is reversed. When the valve is energized, the diaphragm presses down to close the fluid path.

3-way isolation valves have three ports referred to as normally closed, normally open and common. When the valve is de-energized, fluid flows between the normally open and the common port. When the valve is energized, the valve switches and fluid flows between the normally closed and the common port.

Bio-Chem Valve™ Isolation Valves identify the preferred inlet port on the valve label. However, all valves can be used in any flow direction.